{"id":53099,"date":"2026-05-18T11:45:57","date_gmt":"2026-05-18T09:45:57","guid":{"rendered":"https:\/\/iwater.dk.web05.webtohosting.dk\/senfoelger-angst-og-molekylaer-hydrogen\/"},"modified":"2026-09-09T15:36:43","modified_gmt":"2026-09-09T13:36:43","slug":"senfoelger-angst-og-molekylaer-hydrogen","status":"publish","type":"post","link":"https:\/\/iwater.dk\/en\/artikel\/forskning\/senfoelger-angst-og-molekylaer-hydrogen\/","title":{"rendered":"Late complications, anxiety and molecular hydrogen"},"content":{"rendered":"<h2 class=\"wp-block-heading\">Olga Pol is a Spanish neuropsychologist who has researched the emotional and cognitive consequences of chronic pain.<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">When the body remembers what the mind tries to forget<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">For many, a new and often incomprehensible phase begins, characterized by pain, fatigue, sleep problems, concentration difficulty, internal restlessness, and anxiety. Many describe it as a feeling that the body is still on high alert.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">It is precisely this biological state that the Spanish neuropharmacologist and pain researcher Olga Pol has dedicated large parts of her research to understand.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">When pain affects the whole person<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Olga Pol's research shows that chronic pain is not just about tissue damage or damaged nerves. Long-term pain affects the entire nervous system and changes the way the brain processes both physical and emotional signals.<br>Olga Pol's research shows that chronic pain is not just about tissue damage or damaged nerves. Long-term pain affects the entire nervous system and changes the way the brain processes both physical and emotional signals. \n<br>When pain persists, the following are often seen:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Increased oxidative stress<\/li>\n\n\n\n<li>Chronic inflammation<\/li>\n\n\n\n<li>Overactivation of the stress system<\/li>\n\n\n\n<li>Disruptions in neurotransmitters such as serotonin and dopamine<\/li>\n\n\n\n<li>Increased sensitivity in the pain pathways<\/li>\n\n\n\n<li>Anxiety and depressive symptoms<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph translation-block\">Pain and anxiety are therefore closely connected. \n<br>This does not mean that the symptoms are imaginary. It means that the entire organism \u2013 nervous system, immune system, and brain \u2013 is under biological strain.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/iwater.dk\/wp-content\/uploads\/angst-tegning.avif\" alt=\"\"\/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Late complications \u2013 when the body remains on high alert<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Late complications are seen in many people after cancer treatment, autoimmune diseases, major surgeries, infections, and prolonged physical or psychological stress.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">One of the most well-known late complications after chemotherapy is peripheral neuropathy, where the nerves in the hands and feet are damaged. Symptoms can include burning pain, sensory disturbances, sleep disorders, anxiety, and reduced quality of life.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Olga Pol's research has helped document that these symptoms are not merely local nerve damage, but an expression of a deeper dysregulation throughout the entire nervous system.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Research into hydrogen and the nervous system<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Olga Pol and her research group have investigated the effects of hydrogen-rich water and hydrogen therapy in animal models with neuropathic pain and chemotherapy-induced late complications.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The results showed that hydrogen could:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Reduce pain sensitivity<\/li>\n\n\n\n<li>Dampen anxiety-like behaviour<\/li>\n\n\n\n<li>Decrease depressive symptoms<\/li>\n\n\n\n<li>Improve memory and learning<\/li>\n\n\n\n<li>Reduce oxidative stress<\/li>\n\n\n\n<li>Normalize inflammation in the nervous system<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">The research suggests that hydrogen not only affects the pain itself, but also the emotional and cognitive consequences of chronic illness.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Why hydrogen may be relevant for late complications<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">When cellular energy production is weakened and the nervous system is constantly activated, the body can have difficulty returning to a state of calm and regeneration, and here hydrogen appears to be able to support the body's own regulation by protecting the mitochondria, dampening inflammation, reducing oxidative damage, and supporting the balance of the nervous system.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Anxiety as a biological signal<\/h2>\n\n\n\n<p class=\"wp-block-paragraph translation-block\">Anxiety is often perceived as a psychological problem, but in many people with late complications, anxiety is a natural consequence of an overloaded nervous system. \n<br>When the brain registers persistent inflammation and oxidative stress, it can remain in a constant state of alert.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Molecular hydrogen is not a substitute for medical or psychological treatment, but research suggests that it can support the biological processes underlying pain, restlessness, and mental overload.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Molecular hydrogen (H2) is the smallest molecule in the universe. Due to its small size, hydrogen can diffuse rapidly through cell membranes and reach into both the mitochondria and the brain, and hydrogen is particularly interesting because it selectively neutralizes the most harmful free radicals, especially the hydroxyl radical and peroxy nitrite, without disrupting the body's normal redox signalling.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">At the same time, hydrogen affects a number of biological signalling pathways that are central to the body's ability to repair and restore balance.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\u201cThis treatment can alleviate not only the pain caused by a nerve injury, but also the states of anxiety and depression that accompany it.\u201d Quote Olga Pol 2025<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">At iWater Denmark, we have more than 12 years of experience with hydrogen water and hydrogen therapy. Over the years, we have met many people who, after a cancer treatment, have struggled with both physical and psychological late complications such as fatigue, pain, sleep problems, concentration difficulty, restlessness, and anxiety.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Our experience is that many former cancer patients find that molecular hydrogen can be a valuable support in the process of gradually regaining energy, calm, and quality of life. By drinking hydrogen-rich water or inhaling molecular hydrogen, the body gains access to a small, biologically active molecule that easily diffuses into the cells and supports the body's own ability to protect and regulate itself.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Many report that over time they experience better sleep, less restlessness, fewer pains, and a greater sense of physical and mental surplus. This allows them to slowly return to everyday life and to a life with more energy and balance.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">At the same time, a growing amount of research points out that molecular hydrogen can reduce oxidative stress, dampen inflammation, and protect both the nervous system and the mitochondria \u2013 the small energy factories in the cells. It is precisely these mechanisms that are considered to play a central role in the development of many late complications after illness and treatment.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Molecular hydrogen is not a substitute for medical treatment, but in our assessment, it represents a highly interesting and gentle supplement that can support the body's natural ability to find calm, strength, and biological balance again.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Book en online samtale p\u00e5 <a href=\"https:\/\/iwd.dk\/book\" data-type=\"link\" data-id=\"https:\/\/iwd.dk\/book\" target=\"_blank\" rel=\"noreferrer noopener\">iwd.dk\/book<\/a><\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">Scientific references<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Negrini-Ferrari, S. E., Mart\u00ednez-Martel, I., &amp; Pol, O. (2026). Molecular Hydrogen Reverses Nociplastic Pain and Depressive-like Behaviors via Region- and Sex-Dependent Central Mechanisms. International Journal of Molecular Sciences, 27(7), 3051. <br>https:\/\/doi.org\/10.3390\/ijms27073051<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Mart\u00ednez-Serrat, M., Mart\u00ednez-Martel, I., Coral-P\u00e9rez, S., Bai, X., Batall\u00e9, G., &amp; Pol, O. (2022). Hydrogen-Rich Water as a Novel Therapeutic Strategy for the Affective Disorders Linked with Chronic Neuropathic Pain in Mice. MDPI Antioxidants, 11(9), 1826. <br>https:\/\/doi.org\/10.3390\/antiox11091826<\/p>","protected":false},"excerpt":{"rendered":"<p>When a person has been through cancer, serious illness, surgery, or prolonged stress, healing does not always end the day the treatment is over.<\/p>","protected":false},"author":1,"featured_media":53098,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"_kad_post_classname":"","footnotes":""},"categories":[284],"tags":[],"ambassador_emne":[],"class_list":["post-53099","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-forskning"],"acf":[],"taxonomy_info":{"category":[{"value":284,"label":"Forskning"}]},"featured_image_src_large":["https:\/\/iwater.dk\/wp-content\/uploads\/angst-smerter.avif",1024,768,false],"author_info":{"display_name":"webto","author_link":"https:\/\/iwater.dk\/en\/author\/webto\/"},"comment_info":0,"category_info":[{"term_id":284,"name":"Forskning","slug":"forskning","term_group":0,"term_taxonomy_id":284,"taxonomy":"category","description":"Forskning i molekyl\u00e6r hydrogen\r\nL\u00e6s den nyeste forskning om hydrogeninhalation og hydrogenrigt vand. Bliv klogere p\u00e5 forskning om sundhed, velv\u00e6re og optimeret energi.\u00a0I dag bliver der forsket intensivt i hydrogens forbedrende egenskaber p\u00e5 en lang r\u00e6kke sygdomme og helbredsm\u00e6ssige udfordringer. Siden 2007 har der v\u00e6ret stigende interesse for brugen af molekyl\u00e6r hydrogen som terapi til fysiske og psykiske udfordringer. Hydrogen viser hele tiden nye sider af sig selv, s\u00e5 mulighed for dets brug udvider sig.\r\n\r\nForskningens utrolige opdagelser\r\nI 1975 blev der forsket f\u00f8rste gange i hydrogens muligt effekt p\u00e5 menneskets sundhed. Forskerne fandt ud af, at hydrogenterapi var effektivt i forhold til at reducere kr\u00e6fttumorer hos mus. Efter en lang pause, kom der i 2007 kom der igen ny forskning. Fors\u00f8get havde banebrydende resultater, der virkelig satte gang i mulighederne for hydrogenterapi som behandlingsmetode.\r\nEt japansk forskningsstudie viste, at molekyl\u00e6r hydrogen kunne bek\u00e6mpe frie radikaler i cellerne og derfor ogs\u00e5 reducere oxidativ stress. Siden da har \u00a0der har v\u00e6ret massiv interesse. I dag findes er der mere en 1500 forskningsartikler p\u00e5 omr\u00e5det. Interessen er konstant stigende.\r\nNy forskning indikerer blandt andet, at molekyl\u00e6r hydrogen stimulerer vores parasympatiske nervesystem og derudover ogs\u00e5 h\u00e6mmer det sympatiske nervesystem. Det betyder alts\u00e5, at det kan hj\u00e6lpe ogs\u00e5 med at slappe af og bringe niveauet af stress ned. Molekyl\u00e6r hydrogen er nemlig ekstraordin\u00e6r, fordi den kan gennemtr\u00e6nge blod-hjernebarrieren. Da hydrogen er den mindste og kraftigste antioxidant. Derfor kan den tr\u00e6nge ind i mitokondrierne og reparere steder, hvor andre antioxidanter ikke kan n\u00e5 ind.","parent":0,"count":20,"filter":"raw","term_order":"0","cat_ID":284,"category_count":20,"category_description":"Forskning i molekyl\u00e6r hydrogen\r\nL\u00e6s den nyeste forskning om hydrogeninhalation og hydrogenrigt vand. Bliv klogere p\u00e5 forskning om sundhed, velv\u00e6re og optimeret energi.\u00a0I dag bliver der forsket intensivt i hydrogens forbedrende egenskaber p\u00e5 en lang r\u00e6kke sygdomme og helbredsm\u00e6ssige udfordringer. Siden 2007 har der v\u00e6ret stigende interesse for brugen af molekyl\u00e6r hydrogen som terapi til fysiske og psykiske udfordringer. Hydrogen viser hele tiden nye sider af sig selv, s\u00e5 mulighed for dets brug udvider sig.\r\n\r\nForskningens utrolige opdagelser\r\nI 1975 blev der forsket f\u00f8rste gange i hydrogens muligt effekt p\u00e5 menneskets sundhed. Forskerne fandt ud af, at hydrogenterapi var effektivt i forhold til at reducere kr\u00e6fttumorer hos mus. Efter en lang pause, kom der i 2007 kom der igen ny forskning. Fors\u00f8get havde banebrydende resultater, der virkelig satte gang i mulighederne for hydrogenterapi som behandlingsmetode.\r\nEt japansk forskningsstudie viste, at molekyl\u00e6r hydrogen kunne bek\u00e6mpe frie radikaler i cellerne og derfor ogs\u00e5 reducere oxidativ stress. Siden da har \u00a0der har v\u00e6ret massiv interesse. I dag findes er der mere en 1500 forskningsartikler p\u00e5 omr\u00e5det. Interessen er konstant stigende.\r\nNy forskning indikerer blandt andet, at molekyl\u00e6r hydrogen stimulerer vores parasympatiske nervesystem og derudover ogs\u00e5 h\u00e6mmer det sympatiske nervesystem. Det betyder alts\u00e5, at det kan hj\u00e6lpe ogs\u00e5 med at slappe af og bringe niveauet af stress ned. Molekyl\u00e6r hydrogen er nemlig ekstraordin\u00e6r, fordi den kan gennemtr\u00e6nge blod-hjernebarrieren. Da hydrogen er den mindste og kraftigste antioxidant. Derfor kan den tr\u00e6nge ind i mitokondrierne og reparere steder, hvor andre antioxidanter ikke kan n\u00e5 ind.","cat_name":"Forskning","category_nicename":"forskning","category_parent":0}],"tag_info":false,"_links":{"self":[{"href":"https:\/\/iwater.dk\/en\/wp-json\/wp\/v2\/posts\/53099","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/iwater.dk\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/iwater.dk\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/iwater.dk\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/iwater.dk\/en\/wp-json\/wp\/v2\/comments?post=53099"}],"version-history":[{"count":1,"href":"https:\/\/iwater.dk\/en\/wp-json\/wp\/v2\/posts\/53099\/revisions"}],"predecessor-version":[{"id":61318,"href":"https:\/\/iwater.dk\/en\/wp-json\/wp\/v2\/posts\/53099\/revisions\/61318"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/iwater.dk\/en\/wp-json\/wp\/v2\/media\/53098"}],"wp:attachment":[{"href":"https:\/\/iwater.dk\/en\/wp-json\/wp\/v2\/media?parent=53099"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/iwater.dk\/en\/wp-json\/wp\/v2\/categories?post=53099"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/iwater.dk\/en\/wp-json\/wp\/v2\/tags?post=53099"},{"taxonomy":"ambassador_emne","embeddable":true,"href":"https:\/\/iwater.dk\/en\/wp-json\/wp\/v2\/ambassador_emne?post=53099"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}